Introducing the RApport Bookshelf
Lining up spring break plans for this month? If you’re anything like us, you’re probably looking for a good book to bring along. Welcome to the RApport Bookshelf, where we compile what we consider the most essential reads in biotech and health care.
Movie night with RA Capital’s scientific cartographers
Members of TechAtlas work closely with the Investment Team and our portfolio companies to put data into context, identify breakthroughs, and develop conviction about how to solve particular problems given what we know of all the different technologies in development.
Muckrakers, a righteous senator, and a gene therapy walk into a bar
Ah, the American Old West. Where the buffalo roamed, cowboys fought, and Coke still had cocaine. A LOT of things had cocaine. Only the most vigilant and educated physician or pharmacist could hope to keep harmful or useless drugs off their shelves. And if we can still find physicians prescribing ivermectin for COVID today, imagine how hard finding reliable information must have been back then.
A tale of two healthcare systems
As a Swede who has lived in the United States for ~25 years, I’ve experienced two very different healthcare systems. As a child and young adult, I took free (or nearly free) healthcare for granted. However, when I left Sweden to pursue a graduate degree in the US, I was shocked to realize that the system here is very different. I learned new words like ‘deductible’ and ‘copay’ that were not previously part of my vocabulary.
To succeed, we must prepare ourselves for failure
GentiBio CEO Adel Nada discusses why biotechs should build organizations that allow the kind of “good” failures necessary for striking into the unknown and forming the foundations of success. To do so, we must foster cultures that prepare us for, and prepare us to learn from, the field’s inevitable setbacks.
New year, new biotech job? Make sure you understand the value of your equity.
The biotech job market is hotter than ever and it’s not likely to cool down in 2022. So if you’re thinking about joining the Great Resignation and jumping into a new role at a biotech startup, it’s crucial to learn how to think about valuing competing equity offers.
RApport in 2021
In case you missed it (or if you’d like to send a link to a colleague), we’ve compiled a list of RApport’s most popular stories of 2021, along with a few things we’ll be reading over our end-of-year break.
I fixed video conferences. Now Zoom just needs to listen to me.
As the Omicron variant looms over this holiday season, an increasing number of companies are pushing back return-to-office plans (again). What does this mean for all of us? Another year of Zoom. And, Zoom, after spending almost two years “working” on your platform, I have some notes.
Biotech and ESG: Does saving lives get you extra credit? (and other musings)
Growing emphasis on ESG may be a net positive, but how do individual companies allocate resources toward tracking, reporting, or implementing additional practices when those resources might be better spent on their core business that is inherently ESG-focused?
Strongest investors around? Inner City Weightlifting thinks so.
RA Capital teams swept first and second place in Inner City Weightlifting’s “2021 Fittest Company Challenge.” How’d we do it? Because our teams embodied so many of the values that make RA Capital great.
Vaccines and the inverted capital dilemma
Covid has flooded a barren vaccine startup landscape with capital. And that has revealed some valuable lessons for investors, company builders, Congress, and the public.
Innovation thrives in the spotlight
The story of Alexander Fleming is a popular one. As it should be - it’s a good story about one of the most important discoveries in medical history, penicillin. But most people only know the first act of the play.
And now for something completely different
LENZ Therapeutics CEO Eef Schimmelpennink spoke with RApport about how last year’s acquisition of Pfenex by Ligand gave him a chance to seek out a new challenge, the benefits of breaking the mold, and helping 120 million Americans ditch their reading glasses.
Good or just successful? The Belichick conundrum
In biotech - an industry where companies live or die by the success of a lead asset - how much impact does a successful management team have? And more broadly, how should we define success? Is it a matter of stock price? The ability to drive an acquisition? Do your employees even like you as a person?
After binging on COVID-19, what have we missed?
Given the seemingly endless supply of COVID-19-related content, it has sometimes felt like I was passively binging on round-the-clock coverage that was more distracting than edifying. So what might I have missed while I was absorbed in COVID? As it turns out, quite a lot.
Investors and academics: making beautiful music together
Interest in life science technologies and tools is accelerating with the advent of CRISPR and other aspects of synthetic biology. The ability to have a capital efficient way to advance these innovations is very attractive and will help drive innovation.
Accelerating life science tools R&D with venture studios
Interest in life science technologies and tools is accelerating with the advent of CRISPR and other aspects of synthetic biology. The ability to have a capital efficient way to advance these innovations is very attractive and will help drive innovation.
Four core principles for biotech board meetings
There are many ways to conduct an efficient board meeting, and every management team and board member has different preferences. But here are four key principles I believe will improve everyone’s experience.
How to assassinate your start-up: a legal guide
To be sure, none of these can ensure death with dignity, but most will speed your start-up’s demise – especially when taken as combination therapy.
Venture capital evolved to venture creation. Will it stay that way?
The so-called venture creation model has fully taken root, underpinned and enabled by biotech's longest-ever boom cycle and unprecedented sums of available capital.